Prurigo nodularis
☆ AI Dermatology — Free Service
I 2022 Stiftung Warentest-resultaterne fra Tyskland var forbrugernes tilfredshed med ModelDerm kun lidt lavere end med betalte telemedicinske konsultationer.
I 2022 Stiftung Warentest-resultaterne fra Tyskland var forbrugernes tilfredshed med ModelDerm kun lidt lavere end med betalte telemedicinske konsultationer.
relevance score : -100.0%
ReferencesPrurigo nodularis er en kronisk hudlidelse, der er karakteriseret ved flere faste knopper og knuder, som typisk forekommer på de ydre dele af arme og ben. Disse knopper kan variere i farve fra kødtonet til lyserød og er intenst kløende. Tilstanden kan forekomme i alle aldersgrupper og er ofte forbundet med andre hudsygdomme, der giver kronisk kløe, såsom atopisk dermatitis. Behandlingsmuligheder omfatter kraftige anti‑kløe‑mediciner, immunmodulerende lægemidler og lægemidler, der virker på nervesystemet. Håndtering af prurigo nodularis kræver som regel langvarig behandling.
Prurigo nodularis is a chronic disorder of the skin that is classically seen as multiple, firm, flesh to pink colored papules, plaques and nodules commonly located on the extensor surfaces of the extremities. The lesions are very pruritic and can occur in any age group. It is commonly associated with another disease such as atopic dermatitis or any dermatoses associated with chronic pruritus. The therapeutic approach is wide-arrayed ranging from treatments that act as - potent antipruritics, immunomodulators, and neuromodulators. Treatment in an established case is prolonged and improving patient compliance with education and counseling is important.
Prurigo nodularis is a chronic disorder of the skin that is classically seen as multiple, firm, flesh to pink colored papules, plaques and nodules commonly located on the extensor surfaces of the extremities. The lesions are very pruritic and can occur in any age group. It is commonly associated with another disease such as atopic dermatitis or any dermatoses associated with chronic pruritus. The therapeutic approach is wide-arrayed ranging from treatments that act as - potent antipruritics, immunomodulators, and neuromodulators. Treatment in an established case is prolonged and improving patient compliance with education and counseling is important.
Behandling involverer normalt brug af cremer eller injektioner af steroider på det berørte område. I mere alvorlige eller genstridige tilfælde kan det være nødvendigt med behandlinger såsom lysterapi eller medicin, der undertrykker immunsystemet. Thalidomid og lenalidomid er muligheder i alvorlige tilfælde, men de kan have alvorlige bivirkninger. Nyere behandlinger (opioid receptor antagonists, neurokinin-1 receptor antagonists) viser lovende resultater i behandlingen af prurigo nodularis med færre bivirkninger sammenlignet med thalidomid eller lenalidomid.
Treatment typically relies on the use of topical or intralesional steroids, though more severe or recalcitrant cases often necessitate the use of phototherapy or systemic immunosuppressives. Thalidomide and lenalidomide can both be used in severe cases; however, their toxicity profile makes them less favorable. Opioid receptor antagonists and neurokinin-1 receptor antagonists represent two novel families of therapeutic agents which may effectively treat PN with a lower toxicity profile than thalidomide or lenalidomide.
Treatment typically relies on the use of topical or intralesional steroids, though more severe or recalcitrant cases often necessitate the use of phototherapy or systemic immunosuppressives. Thalidomide and lenalidomide can both be used in severe cases; however, their toxicity profile makes them less favorable. Opioid receptor antagonists and neurokinin-1 receptor antagonists represent two novel families of therapeutic agents which may effectively treat PN with a lower toxicity profile than thalidomide or lenalidomide.
Chronic prurigo er en hudlidelse, der er karakteriseret ved langvarig kløe (varende over 6 uger), ridserelaterede hudlæsioner og en historie med hyppige kradsninger. Tilstanden involverer neuroinflammation og fibrose i huden.
Chronic prurigo (CPG) is a neuroinflammatory, fibrotic dermatosis that is defined by the presence of chronic pruritus (itch lasting longer than 6 weeks), scratch-associated pruriginous skin lesions and history of repeated scratching.
Chronic prurigo (CPG) is a neuroinflammatory, fibrotic dermatosis that is defined by the presence of chronic pruritus (itch lasting longer than 6 weeks), scratch-associated pruriginous skin lesions and history of repeated scratching.
Prurigo nodularis er et langvarigt hudproblem præget af kløende knuder. Vi ved ikke præcis, hvad der forårsager den, men det ser ud til, at immun‑ og nerveproblemer spiller en rolle i kløe‑ridse‑cyklussen. Lige nu er der ingen behandlinger, der er godkendt af US FDA specifikt til Prurigo nodularis.
Prurigo nodularis is a long-lasting skin problem marked by itchy nodules. We don't know exactly what causes it, but it seems that immune and nerve issues play a role in the itch-scratch cycle. Right now, there aren't any treatments approved by the US FDA specifically for prurigo nodularis.
Prurigo nodularis is a long-lasting skin problem marked by itchy nodules. We don't know exactly what causes it, but it seems that immune and nerve issues play a role in the itch-scratch cycle. Right now, there aren't any treatments approved by the US FDA specifically for prurigo nodularis.
○ Behandling – OTC‑lægemidler
Vask af læsionsområdet med sæbe hjælper slet ikke og kan forværre tilstanden. OTC‑steroidsalver kan lindre symptomerne, men de skal normalt anvendes i flere uger, før der ses forbedring. Fortsat brug af antihistaminer kan også lindre kløen.
#OTC steroid ointment
#OTC antihistamine
○ Behandling
#Intralesional triamcinolone injection